carboxypeptidase a — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T76167	Carboxypeptidase A
	Carboxypeptidase A (EC 3.4.2.1), a zinc-containing metalloprotease, catalyzes the hydrolysis of peptide bonds near the C-terminal end of polypeptides and is frequently utilized in biochemical research. As a prototypical ...
T16116	MLN-4760		RAAS
	MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypept...		RAAS
T10678	Carboxypeptidase G2 (CPG2) Inhibitor	CPG2 Inhibitor,Carboxypeptidase G2 Inhibitor	Carboxypeptidase
	Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.		Carboxypeptidase
T10876	CPA inhibitor	Carboxypeptidase inhibitor	Carboxypeptidase
	CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.		Carboxypeptidase
T3440	2-PMPA	2-(Phosphonomethyl)pentanedioic acid	Carboxypeptidase
	2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).		Carboxypeptidase
T69327	E2072
	E2072 is a potent and selective thiol-based Glutamate Carboxypeptidase II (GCP-II) inhibitor.
T25968	PMPA sodium	PMPA sodium salt,PMPA tetrasodium salt,PMPA Na
	PMPA sodium is a potent and selective glutamate carboxypeptidase 2 (GCP II/N-acetylated a-linked dipeptidase/NAALADase) inhibitor.
T26725	AZD-9684	AZD9684,AZD 9684
	AZD-9684, a carboxypeptidase U inhibitor, is used potentially for the prevention of thrombosis.
T62423	GCPII-IN-1 TFA
	GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII; PSMA) inhibitor scaffold (Ki: 44.3 nM).
TP2076	[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
	Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin in vivo.
T80113	Bz-Ala-Arg		Endogenous Metabolite
	Bz-Ala-Arg, a dipeptide, serves as a spectrophotometric substrate (0.4 M pyridine formate, pH 4.25) for human pancreatic carboxypeptidase B and plasma carboxypeptidase N. It is utilized to screen for competitive inhibito...		Endogenous Metabolite
T76102	Carboxypeptidase B
	Carboxypeptidase B, a peptide exonuclease, specifically degrades peptide chains by progressively hydrolyzing from the C-terminal, releasing free amino acids. It acts exclusively on peptide bonds with basic amino acids (s...
TP1747	Bradykinin (1-6)
	Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).Bradykinin (1-6) is a fragment of bradykinin. Bradykinin activates pai...
T38420	GCPII-IN-1
	GCPII-IN-1 is a potent inhibitor scaffold targeting glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA). It exhibits a high affinity for GCPII, with a binding affinity (K i ) of...
T78239	Mergetpa		Carboxypeptidase
	Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].		Carboxypeptidase
T75118	AN15368
	AN15368, an orally administered small-molecule precursor, undergoes activation by parasite carboxypeptidase, yielding a product that interferes with the messenger RNA processing pathway in T. cruzi. This compound shows p...
T82286	Glycylglycylcysteine
	Glycylglycylcysteine is an inhibitor of Thrombin Activatable Fibrinolysis Inhibitor (TAFI), exhibiting a K_i value of 0.99 µM and an IC_50 of 9.4 µM in TAFI substrate assays. TAFI, a basic carboxypeptidase, hinders fibri...
T80114	FA-Ala-Arg		Endogenous Metabolite
	FA-Ala-Arg is a dipeptide featuring a furylacryloyl group that degrades to yield arginine. It augments nitric oxide (NO) synthesis in MCF-7 cells through a mechanism in which cell-surface Carboxypeptidase-D (CPD) elevate...		Endogenous Metabolite